Introduction: Retinopathy of Pre-maturity (ROP) is one of the leading causes of preventable childhood blindness in India. Neonatologist have been playing the major role to recognize infants for screening ROP and also counsel parents regarding seriousness of issue, possible findings and consequences. Aim: To evaluate the prevalence of Retinopathy of Prematurity (ROP), demographic characteristics and treatment outcomes among infants admitted to the Neonatal Intensive Care Unit (NICU). Material and Methods: A single-centre retrospective hospital based observational study was carried out among infants with screening for ROP performed in all preterm neonates who are born <34 weeks gestation and/or <1750 grams birth weight; as well as in babies 34-36 weeks gestation or 1750-2000 grams birth weight if they have risk factors for ROP. We collected information from Medical Record Department (MRD) through Case Record Form (CRF). The collected data was tabulated and all statistical analysis was performed. Results: 106 were eligible for ROP screening in which 15 infants developed ROP. Out of the 15 infants with ROP, 7 were male and 8 were female. Prevalence of ROP was 14.15%. The mean gestational age was found to be 31.26 weeks and mean birth weight was recorded 1.348 kg. Amongst 15 ROP cases, 12 (80.00%) were classified into classic, 02 (13.34%) into aggressive posterior retinopathy of prematurity (APROP), and 01 (06.66%) into hybrid. Conclusion: Demonstrated high prevalence of APROP which was 13.34%. Successful screening and appropriate action cease the progression of ROP to last stages, for this role of treating pediatrician/ neonatologist, obstetrician and ophthalmologist has become predominant.