Intravenous (IV) fluid and medication infiltrations may result in serious complications such as tissue necrosis, ulcerations, and compartment syndromes. Objectives are to assess the existing and postpractice level skills of staff nurses about the S.T.I.C.K. Bundle and to find out the effectiveness of bundle in terms of improvement in posttest level of practice scores. Research approach was quantitative research approach and research design was pre experimental one group pretest-posttest design. Sample size was 30 and sampling technique was non probability consecutive sampling. Major finds were apparently higher in the post test group in comparison to the pre-test group. The paired ‘t’ test value is found to be 2.16 at the degree of freedom 29 and the corresponding p value is <0.05. Hence, the research hypothesis can be accepted at 5% level of significance and can be inferred that there is significant difference between pre and post-practice level.